منابع مشابه
Wnt Signalling in Gastrointestinal Epithelial Stem Cells.
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Introduction Many scientific meetings have been organized to present research findings on stem-cell sources, their pluripotent nature and potential therapeutic applications for treating disease. The theme of this meeting was the signalling pathways that control stem-cell maintenance and differentiation. In his keynote address, A. Spiegel (Bethesda, MD, USA) emphasized the high therapeutic poten...
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Stem cells in vitro Cell replacement approaches have provided the basis for the development of potentially powerful new therapeutic strategies for a broad spectrum of brain diseases. The rationale of this therapeutic approach relies on transplantation to the central nervous system of cells that are able to replace the lost elements and rewire the disrupted circuitries, thus restoring normal bra...
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Wnt/β-catenin signalling regulates cell fate, survival, proliferation and differentiation at many stages of mammalian development and pathology. Mutations of two key proteins in the pathway, APC and β-catenin, have been implicated in a range of cancers, including colorectal cancer. Activation of Wnt signalling has been associated with the stabilization and nuclear accumulation of β-catenin and ...
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ژورنال
عنوان ژورنال: International Journal of Surgery
سال: 2010
ISSN: 1743-9191
DOI: 10.1016/j.ijsu.2010.07.280